About Us

Our mission

Providing the highest quality veterinary medical diagnostic services for laboratory animal health surveillance, veterinary patient care and research support.

About UsOur history

The development of a lab animal diagnostic laboratory at UC Davis began in the late 80's as part of the Animal Resources Service (ARS) under Dale Brooks. Its main objective was to provide health monitoring for rodent research colonies and diagnostic support for all animals used in research at UC Davis. Dave Knudson, then Rick Ermel followed by Stephen Griffey directed these activities.

In 1998, Stephen Griffey proposed to develop the laboratory animal diagnostic program with a specific emphasis on mouse diagnostics and anatomic phenotyping to serve the needs of not only the School of Veterinary Medicine and UC Davis, but also the other UC laboratory animal programs. There were several other programs developed at UC Davis at this time that also supported the development of the CPL. These included the formation of the Center for Comparative Medicine, the Mouse Biology Program (an NIH Mutant Mouse Regional Resource and Knockout Mouse Phenotyping Center), a UC Davis partnership with The Jackson Laboratory, as well as the needs of the other UC lab animal programs. The Comparative Pathology Laboratory was formalized as a self-supporting service unit in the School of Veterinary Medicine in July 2000.

In July 2018, Denise Imai-Leonard became director of CPL. Her new initiatives have included the restructure of residency/fellowship programs, the development and implementation of zebrafish and xenopus health surveillance programs and the expansion of research pathology services. She has strengthened collaborative ties to the California National Primate Research Center and University of Washington and expanded national and international recognition for the lab animal pathology training program through a web-based platform for pathology rounds.

 

Latest News

Dr. Denise Imai-Leonard Farewell

After 12 years with the Comparative Pathology Laboratory and 7 years as Director, I will be stepping down effective September 30th, 2025. Leading this team has been one of the greatest privileges of my career. I’m deeply grateful to our staff, faculty collaborators, SVM leaders, campus partners, and valued clients for our shared commitment to excellence, on behalf of the animals in teaching and research and the scientific breakthroughs that we all help to advance.

Highlighting the Vital Role of In situ Molecular techniques in Biomedical Research

The Comparative Pathology Laboratory has invited Dr. Sharon Yang from the Translational Pathology Shared Resource at Vanderbilt University Medical Center to speak at the Biomedical Research Awareness Day at UC Davis on April 18th. Dr. Yang will be summarizing in situ molecular techniques (immunofluorescence, immunohistochemistry, in situ hybridization) and discussing comparative strengths and limitations, approaches to validating biomarkers, and impact on research outcomes.

Advocacy for Veterinary Education: Addressing Faculty Shortages and Future Needs

ADVOCACY DAY 2024. Denise Imai-Leonard, Director of the Comparative Pathology Laboratory, went to Capitol Hill to advocate for the future of veterinary medical education with Dean Stetter of UC Davis and Dean Tegzes, Executive Associate Dean McClure and Director Diniz from Western University. The need is pressing. Access to care, food safety, animal welfare, pandemic prevention, medical innovation, environmental health and conservation, are only a few spaces in which veterinarians are critically needed.